[Efficiency of influenza vaccination in the working population in Spain].
Identifieur interne : 000583 ( Main/Exploration ); précédent : 000582; suivant : 000584[Efficiency of influenza vaccination in the working population in Spain].
Auteurs : José Ram N De Juanes [Espagne] ; Ram N Cisterna ; Javier Sanz ; Sol Magaz ; Xavier BadiaSource :
- Gaceta sanitaria [ 0213-9111 ]
Descripteurs français
- KwdFr :
- MESH :
- prévention et contrôle : Grippe humaine.
- économie : Vaccins antigrippaux.
- Adolescent, Adulte, Adulte d'âge moyen, Analyse coût-bénéfice, Espagne, Femelle, Humains, Mâle, Santé au travail, Sujet âgé.
- Wicri :
- geographic : Espagne.
English descriptors
- KwdEn :
- MESH :
- chemical , economics : Influenza Vaccines.
- geographic : Spain.
- prevention & control : Influenza, Human.
- Adolescent, Adult, Aged, Cost-Benefit Analysis, Female, Humans, Male, Middle Aged, Occupational Health.
Abstract
INTRODUCTION
Influenza is a major cause of morbidity and mortality worldwide. Currently, licensed influenza vaccines are safe and effective. Any intervention aimed at reducing the burden of illness is worth analyzing from a clinical and economic perspective.
OBJECTIVE
To assess the costs and benefits of an influenza vaccination program in the Spanish working population.
METHODS
A theoretical model of costs and benefits in terms of productivity savings was developed to compare 2 strategies (vaccination and non-vaccination) in 2 cohorts of 1,000 workers each. The time horizon was 1 year and the study's perspective was societal.
MAIN OUTCOME MEASURES
epidemiological and clinical data on the incidence of influenza and the effectiveness of the vaccine. Data on the use of direct and indirect resources were obtained from an expert panel of 5 experts in preventive medicine, microbiology, occupational health, and health economics. Unit costs (euros 2003) were extracted from local databases. A sensitivity analysis was performed with the data on incidence, effectiveness, and work absenteeism due to influenza.
RESULTS
In the base case scenario, influenza vaccine saved 35 Euros per worker, of which 88% were savings in work loss days avoided. Threshold values in the sensitivity analysis were 6% for the incidence of influenza and 1.5 days for absence from work, above which the vaccine leads to net savings.
CONCLUSIONS
Influenza vaccination in the Spanish working population might result in net resource savings to society at large.
DOI: 10.1157/13087326
PubMed: 16753086
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Sanz</name></author><author><name sortKey="Magaz, Sol" sort="Magaz, Sol" uniqKey="Magaz S" first="Sol" last="Magaz">Sol Magaz</name></author><author><name sortKey="Badia, Xavier" sort="Badia, Xavier" uniqKey="Badia X" first="Xavier" last="Badia">Xavier Badia</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2006">2006 Mar-Apr</date><idno type="RBID">pubmed:16753086</idno><idno type="pmid">16753086</idno><idno type="doi">10.1157/13087326</idno><idno type="wicri:Area/Main/Corpus">00596</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">00596</idno><idno type="wicri:Area/Main/Curation">000596</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000596</idno><idno type="wicri:Area/Main/Exploration">000596</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Efficiency of influenza vaccination in the working population in Spain].</title><author><name sortKey="De Juanes, Jose Ram N" sort="De Juanes, Jose Ram N" uniqKey="De Juanes J" first="José Ram N" last="De Juanes">José Ram N De Juanes</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Medicina Preventiva, Hospital 12 de Octubre, Madrid, España.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Medicina Preventiva, Hospital 12 de Octubre, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Cisterna, Ram N" sort="Cisterna, Ram N" uniqKey="Cisterna R" first="Ram N" last="Cisterna">Ram N Cisterna</name></author><author><name sortKey="Sanz, Javier" sort="Sanz, Javier" uniqKey="Sanz J" first="Javier" last="Sanz">Javier Sanz</name></author><author><name sortKey="Magaz, Sol" sort="Magaz, Sol" uniqKey="Magaz S" first="Sol" last="Magaz">Sol Magaz</name></author><author><name sortKey="Badia, Xavier" sort="Badia, Xavier" uniqKey="Badia X" first="Xavier" last="Badia">Xavier Badia</name></author></analytic><series><title level="j">Gaceta sanitaria</title><idno type="ISSN">0213-9111</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term><term>Adult (MeSH)</term><term>Aged (MeSH)</term><term>Cost-Benefit Analysis (MeSH)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Influenza Vaccines (economics)</term><term>Influenza, Human (prevention & control)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Occupational Health (MeSH)</term><term>Spain (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Analyse coût-bénéfice (MeSH)</term><term>Espagne (MeSH)</term><term>Femelle (MeSH)</term><term>Grippe humaine (prévention et contrôle)</term><term>Humains (MeSH)</term><term>Mâle (MeSH)</term><term>Santé au travail (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Vaccins antigrippaux (économie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="economics" xml:lang="en"><term>Influenza Vaccines</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Spain</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" qualifier="économie" xml:lang="fr"><term>Vaccins antigrippaux</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Cost-Benefit Analysis</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Occupational Health</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Analyse coût-bénéfice</term><term>Espagne</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Santé au travail</term><term>Sujet âgé</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>INTRODUCTION</b></p><p>Influenza is a major cause of morbidity and mortality worldwide. Currently, licensed influenza vaccines are safe and effective. Any intervention aimed at reducing the burden of illness is worth analyzing from a clinical and economic perspective.</p></div><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>To assess the costs and benefits of an influenza vaccination program in the Spanish working population.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>A theoretical model of costs and benefits in terms of productivity savings was developed to compare 2 strategies (vaccination and non-vaccination) in 2 cohorts of 1,000 workers each. The time horizon was 1 year and the study's perspective was societal.</p></div><div type="abstract" xml:lang="en"><p><b>MAIN OUTCOME MEASURES</b></p><p>epidemiological and clinical data on the incidence of influenza and the effectiveness of the vaccine. Data on the use of direct and indirect resources were obtained from an expert panel of 5 experts in preventive medicine, microbiology, occupational health, and health economics. Unit costs (euros 2003) were extracted from local databases. A sensitivity analysis was performed with the data on incidence, effectiveness, and work absenteeism due to influenza.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>In the base case scenario, influenza vaccine saved 35 Euros per worker, of which 88% were savings in work loss days avoided. Threshold values in the sensitivity analysis were 6% for the incidence of influenza and 1.5 days for absence from work, above which the vaccine leads to net savings.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Influenza vaccination in the Spanish working population might result in net resource savings to society at large.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">16753086</PMID><DateCompleted><Year>2006</Year><Month>08</Month><Day>30</Day></DateCompleted><DateRevised><Year>2019</Year><Month>09</Month><Day>22</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0213-9111</ISSN><JournalIssue CitedMedium="Print"><Volume>20</Volume><Issue>2</Issue><PubDate><MedlineDate>2006 Mar-Apr</MedlineDate></PubDate></JournalIssue><Title>Gaceta sanitaria</Title><ISOAbbreviation>Gac Sanit</ISOAbbreviation></Journal><ArticleTitle>[Efficiency of influenza vaccination in the working population in Spain].</ArticleTitle><Pagination><MedlinePgn>101-7</MedlinePgn></Pagination><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Influenza is a major cause of morbidity and mortality worldwide. Currently, licensed influenza vaccines are safe and effective. Any intervention aimed at reducing the burden of illness is worth analyzing from a clinical and economic perspective.</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To assess the costs and benefits of an influenza vaccination program in the Spanish working population.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A theoretical model of costs and benefits in terms of productivity savings was developed to compare 2 strategies (vaccination and non-vaccination) in 2 cohorts of 1,000 workers each. The time horizon was 1 year and the study's perspective was societal.</AbstractText><AbstractText Label="MAIN OUTCOME MEASURES" NlmCategory="METHODS">epidemiological and clinical data on the incidence of influenza and the effectiveness of the vaccine. Data on the use of direct and indirect resources were obtained from an expert panel of 5 experts in preventive medicine, microbiology, occupational health, and health economics. Unit costs (euros 2003) were extracted from local databases. A sensitivity analysis was performed with the data on incidence, effectiveness, and work absenteeism due to influenza.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In the base case scenario, influenza vaccine saved 35 Euros per worker, of which 88% were savings in work loss days avoided. Threshold values in the sensitivity analysis were 6% for the incidence of influenza and 1.5 days for absence from work, above which the vaccine leads to net savings.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Influenza vaccination in the Spanish working population might result in net resource savings to society at large.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>de Juanes</LastName><ForeName>José Ramón</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>Servicio de Medicina Preventiva, Hospital 12 de Octubre, Madrid, España.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cisterna</LastName><ForeName>Ramón</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Sanz</LastName><ForeName>Javier</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Magaz</LastName><ForeName>Sol</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Badia</LastName><ForeName>Xavier</ForeName><Initials>X</Initials></Author></AuthorList><Language>spa</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><VernacularTitle>Evaluación de la eficiencia de la vacunación antigripal en la población laboral española.</VernacularTitle></Article><MedlineJournalInfo><Country>Spain</Country><MedlineTA>Gac Sanit</MedlineTA><NlmUniqueID>8901623</NlmUniqueID><ISSNLinking>0213-9111</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007252">Influenza Vaccines</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003362" MajorTopicYN="N">Cost-Benefit Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007252" MajorTopicYN="N">Influenza Vaccines</DescriptorName><QualifierName UI="Q000191" MajorTopicYN="Y">economics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016272" MajorTopicYN="Y">Occupational Health</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N" Type="Geographic">Spain</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2006</Year><Month>6</Month><Day>7</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2006</Year><Month>8</Month><Day>31</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2006</Year><Month>6</Month><Day>7</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">16753086</ArticleId><ArticleId IdType="pii">13087326</ArticleId><ArticleId IdType="doi">10.1157/13087326</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Espagne</li></country><region><li>Communauté de Madrid</li></region><settlement><li>Madrid</li></settlement></list><tree><noCountry><name sortKey="Badia, Xavier" sort="Badia, Xavier" uniqKey="Badia X" first="Xavier" last="Badia">Xavier Badia</name><name sortKey="Cisterna, Ram N" sort="Cisterna, Ram N" uniqKey="Cisterna R" first="Ram N" last="Cisterna">Ram N Cisterna</name><name sortKey="Magaz, Sol" sort="Magaz, Sol" uniqKey="Magaz S" first="Sol" last="Magaz">Sol Magaz</name><name sortKey="Sanz, Javier" sort="Sanz, Javier" uniqKey="Sanz J" first="Javier" last="Sanz">Javier Sanz</name></noCountry><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="De Juanes, Jose Ram N" sort="De Juanes, Jose Ram N" uniqKey="De Juanes J" first="José Ram N" last="De Juanes">José Ram N De Juanes</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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